An X-linked DraI RFLP recognized by cpX23 [DXS132]
نویسندگان
چکیده
منابع مشابه
RFLP detected by an X-linked cDNA encoding erythroid-potentiating activity/tissue inhibitor of metalloproteinase (EPA/TIMP).
SOURCE/DESCRIPTION: A full length (1.1 kb) human EPA cDNA * clone inserted in p91023(B) at the EcoRI restriction site * (1). POLYMORPHISM: Bglll identifies a two allele polymorphism with • bands of approximately 12 kb (Al) or 9.5 and 2.5-kb (A2). « t FREQUENCY: A total of 102 X chromosomes from 54 unrelated individuals was examined. £ Al (12 kb allele): 0.66 PvuII or Xbal with a panel of three ...
متن کاملBgl II RFLP recognized by a human IRBP cDNA localized to chromosome 10.
SOURCE/DESCRIPTION: A 2184 bp cDNA (H.4 IRBP) encoding human interstitial retinol-binding protein (IRBP; Fong et al., 1984) isolated from a human retina cDNA library in XgtlO by screening with a bovine IRBP cDNA probe (B.23; Liou et al., 1986). POLYMORPHISM: Bgl II (AGATCT) identifies a 2-allele polymorphism with bands at 6.3 kb (A1) and 4.3 kb (A2). There is a strong invariant band at 2.5 kb. ...
متن کاملX-linked retinoschisis: an update.
X-linked retinoschisis is the leading cause of macular degeneration in males and leads to splitting within the inner retinal layers leading to visual deterioration. Many missense and protein truncating mutations have now been identified in the causative retinoschisis gene (RS1) which encodes a 224 amino acid secretory retinal protein, retinoschisin. Retinoschisin octamerisation is implicated in...
متن کاملPrenatal sex determination in suspicious cases of X-linked recessive diseases by the amelogenin gene
Objective(s):To determine the fetal discernment in suspected cases of sex linked recessive disease in the first trimester of pregnancy. Materials and Methods: After collection of 100 Chorionic Villi samples, the DNAs were extracted and baby gender was determined. Meanwhile, after increasing the sensitivity, the system was able to detect the sex of each cell which was obtained by biopsy. Resul...
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ژورنال
عنوان ژورنال: Nucleic Acids Research
سال: 1989
ISSN: 0305-1048,1362-4962
DOI: 10.1093/nar/17.16.6754